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Nanopills release drugs directly from inside cells
Researchers from the Autonomous University of Barcelona (UAB) have created nanoparticles capable of releasing drugs directly from inside cells. The technology, called "nanopills", has been licensed to the company Janus Developments, of the Barcelona Science Park, which has verified its tolerance when administered live.
Researchers at the UAB have developed a new vehicle for releasing proteins with therapeutic effects. Although these inclusion bodies have traditionally been an obstacle to the industrial production of soluble enzymes and biopharmaceuticals, it has recently been recognized that they have large amounts of functional proteins with direct values in industrial and biomedical applications.
The research team led by Antoni Villaverde, from the UAB Institute of Biotechnology and Biomedicine (IBB), worked in collaboration with the Center for Networked Biomedical Research in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) to verify the value of these nanoparticles as natural "nanopills" with a strong ability to penetrate cells and carry biological activities. The nanopill concept represents a promising new platform for drug delivery and illustrates the still unexplored power of microbial materials in medicine.